All Current Investments

3Leaf Systems 3Leaf Systems is developing the infrastructure for virtual servers in the enterprise data center. Santa Clara, CA.
The Active Network The Active Network provides technology application services and marketing access for service and active lifestyle organizations worldwide. San Diego, CA.
Anaborex Anaborex is an early stage biotechnology company developing drugs for the treatment of the wasting syndrome many cancer patients experience towards the late stages of their disease. San Diego, CA.
Ascenta Therapeutics Ascenta Therapeutics is a clinical stage biopharmaceutical company focused on oncology. San Diego, CA.
B.M.S. BMS delivers outsourced specialized billing and financial management services for the physical therapy industry. Upland, CA.
Breach Security Breach Security provides web application security that protects corporate-critical information. Breach products protect commercial enterprises and government agencies web applications against Internet hacking attacks and provide solutions for expanding security challenges such as identity theft, information leakage, and insecurely coded applications Carlsbad, CA.
Calient Networks Calient Networks provides fiber optic cross-connection systems designed to address the needs of telecommunications carriers, large enterprises and research and government organizations. San Jose, CA.
Celladon Celladon is a biotechnology company that develops molecular therapies for the treatment of cardiovascular diseases. La Jolla, CA.
Celula Celula develops innovative instrument systems for esoteric molecular diagnostics using advanced microfluidics technologies. San Diego, California.
Complete Genomics Complete Genomics is a DNA sequencing company developing a method for high throughput DNA sequencing to inexpensively produce a human genome. Sunnyvale, CA.
Devicescape Devicescape provides software and services that make it easy, fast and inexpensive for consumers to access the web via their wireless devices. San Bruno, CA.
Enviance Enviance designs Internet-based environmental compliance solutions. Enviance systems provide complete collection, distribution, analysis and reporting of environmental health and safety data. Carlsbad, CA.
Expresso Fitness Expresso Fitness provides networked and interactive software and cardio equipment for the multi-billion dollar fitness industry. Sunnyvale, CA.
Genoptix Genoptix is a specialized laboratory service for hematologists and oncologists. The company provides personalized medicine services for individual patients. Carlsbad, CA.
Hammerhead Systems Hammerhead Systems provides products that accelerate the profitable delivery of new Ethernet and existing legacy services. Mountain View, CA.
IdenTrust IdenTrust is a global identity authentication company that provides identity solutions recognized and trusted by financial institutions, government agencies and departments, and commercial organizations around the world. San Francisco, CA.
INSPIRIS INSPIRIS is a healthcare management company focused on improving the quality of life for the frail elderly population, while reducing the cost to Medicare Advantage health plans. Brentwood, TN.
Muze Muze provides detailed product information for music, books, films, and games to enable commerce in entertainment media. New York, New York.
NEXX Systems NEXX is a semiconductor company that provides process solutions for advanced packaging, flip chip, wafer level CSP, and LEDs. Billerica, MA.
NP Photonics NP Photonics is an advanced optical company designing and manufacturing narrow line-width lasers, ASE sources, fiber amplifiers and high-power light sources for sensing, medical and R&D markets. Tucson, AZ.
Ophthonix Ophthonix is developing and commercializing a programmable "super lens" capable of delivering 20/10 vision. San Diego, CA.
Pivotal Systems Pivotal Systems is a semiconductor company that provides process control solutions to ensure consistent quality wafer production. Pleasanton, CA.
Quartics Quartics technologies enable seamless wireless communication between a wide array of digital media sources, including laptops, TVs, and projectors.

Irvine, CA.
Quorum Systems Quorum Systems is a fabless semiconductor company that develops highly integrated multi-mode CMOS radio frequency transceivers. San Diego, CA.
ReliOn ReliOn develops and markets modular Proton Exchange Membrane (PEM) fuel cell products. ReliOn products are available globally for commercial and industrial backup applications in the 600-Watt to 12-kilowatt range. Spokane, WA.
The Retail Equation The Retail Equation develops and commercializes return authorization solutions that help prevent customer fraud for the retail industry. Irvine, CA.
Scoperta Scoperta has created a fabless specialty steel technology utilizing scrap materials. The material is exeptionally strong, hard, flexible and resistant to corrosion and deformation. San Diego, CA.
Specific Media Specific Media is a technology and online media company that enables advertisers to pinpoint their target audiences through advanced demographic, behavioral, contextual, geographic and retargeting technologies across a network of branded, top tier sites. Irvine, CA.
TargeGen TargeGen is a biopharmaceutical company that develops targeted therapeutics for treating vascular permeability and leakage associated with such diseases as macular degeneration, heart attacks and cancer. San Diego, CA.
Tensys Medical Tensys has developed a continuous, non-invasive blood pressure monitoring technology for cardiac output assessment that is easy to administer and comfortable for the patient. San Diego, CA.
TradeBeam Holdings TradeBeam is a global trade management software and services company providing solutions that streamline global trading processes for enterprises and their partners. San Mateo, CA.
VMIX Media VMIX is the leading provider of software and services enabling online publishers to deliver video, rich media, social networking, user-generated content and interactive community tools to their online audiences. The VMIX.CORE software platform provides a turnkey solution for media management of videos, audio, photos, and slideshows, with social networking and community features. VMIX is a dedicated innovator and the trusted partner for companies such as Tribune Company, McClatchy Interactive, L San Diego, CA.
WorkWell Systems WorkWell Systems delivers injury prevention, workers compensation management and early intervention stay-at-work/return-to-work programs for employers. San Juan Capistrano, CA.
Xifin Corporation Xifin delivers specialized billing and financial management services for the healthcare industry. Carlsbad, CA.